Dose adjustment in insulin pump therapy: optimization of bolus calculator settings

Precise dosing of insulin at meals and for correction of glycemia is crucial for sustention of optimal blood glucose concentration. Moderninsulin delivery systems (such as insulin pumps) not only provide high dosing precision, but are also capable of calculating necessarydose by means of built-in software - so called bolus calculators. However, patient-oriented approach to calculator settings, as wellas their timely correction is imperative for attainment of desired precision. Though similar in their principle, various calculatorsalso feature essential peculiarities that have to be considered for optimal adjustment. The review addresses current evidence for boluscalculator efficiency, comparative analysis of these applications and description of their key distinctions.