Open AccessDiabetic osteoarthropathy: modern methods of therapy
Author(s) -
Ульянова Ирина Николаевна,
Токмакова Алла Юрьевна,
Ярославцева Марианна Викторовна,
Ильин Александр Викторович,
Галстян Гагик Радикович
Publication year - 2010
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-6061
Subject(s) - medicine , spinal osteoarthropathy , pathogenesis , osteopenia , rheumatoid arthritis , inflammation , orthopedic surgery , resorption , surgery , osteoporosis , bone mineral
This paper is focused on the main aspects of pathogenesis of diabetic osteoarthropathy (DOAP) underlain by motor and sensory neuropathies, injuries(including microfractures and joint disintegration), and inflammation accompanied by enhanced cytokine expression. The role of osteopenia andbone resorption-formation decoupling at different stages of DOAP is discussed. Modern methods of DOAP treatment are considered with special referenceto immobilization, drug therapy, surgical and orthopedic care