Open AccessNecrobiosis lipoidica in diabetic patients: pathogenetic and clinical features
Author(s) -
Daria A. Semenova,
Alla Yur'evna Tokmakova
Publication year - 2011
Publication title -
diabetes mellitus
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-5817
Subject(s) - necrobiosis lipoidica , medicine , vitiligo , sarcoidosis , diabetes mellitus , disease , dermatology , thyroid disease , psoriasis , population , thyroid , immunology , endocrinology , environmental health
Necrobiosis lipoidica (NL) is a chronic skin disease (dermatosis) associated with various metabolic disorders including carbohydrate metabolism.In the last years, NL has been increasingly frequently diagnosed by practitioners probably due to the rise in type 2 diabetes mellitus morbidity in thegeneral population. Moreover, association of NL with autoimmune thyroid diseases, Crohns disease, ulcerative colitis, sarcoidosis, and vitiligo hasbeen documented. Such cases may be attributed to phenotypic and functional defects of cellular immunity.
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