Open AccessThe influence of diabetic autonomous neuropathy on myocardial remodeling in type 1 diabetes mellitus
Author(s) -
Ирина Аркадьевна Бондарь,
Бондарь Ирина Аркадьевна,
Elena A. Koroleva,
Королева Елена Анатольевна,
Olga Grigor'evna Chudinova,
Чудинова Ольга Григорьевна
Publication year - 2011
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-5634
Subject(s) - medicine , cardiology , interventricular septum , ventricle , left ventricular hypertrophy , diabetes mellitus , muscle hypertrophy , diastole , type 2 diabetes mellitus , myocardial hypertrophy , ventricular remodeling , blood pressure , heart failure , endocrinology
Aim. To assess the influence of diabetic autonomous neuropathy (DAN) on left ventricular myocardial remodeling in type 1 diabetes mellitus. Materials and methods. The study included 78 patients (30 men and 48 women) with DM1 (mean age 28.9?8.3 years, DM1 duration9.7?7.5 years). DAN was diagnosed by standard ECG tests (Valsalva and breathing tests). The patients were examined using echocardiographywith the measurement of the thickness of interventricular septum (IVS) and left ventricle posterior wall (PW), end diastolic and systolic size (EDS and ESS) of the left ventricle, left ventricular myocardial mass (MM), MM index and relative wall thickness (RWT). LV hypertrophy(LVH) was diagnosed at MM index ?134 g/m2 in men and ?110 g/m2 in women; concentric and excentric types of LV hypertrophy wererecorded at RWT ?0.45 and