Open AccessGlycated hemoglobin test: diagnostic difficulties in gestational diabetes
Author(s) -
Татьяна Владимировна Саприна,
Саприна Татьяна Владимировна,
Екатерина Сергеевна Тимохина,
Тимохина Екатерина Сергеевна,
И. Н. Ворожцова,
Ворожцова Ирина Николаевна
Publication year - 2012
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-5540
Subject(s) - medicine , glycemic , glycated hemoglobin , gestational diabetes , diabetes mellitus , pregnancy , hemoglobin , gastroenterology , anemia , glucose tolerance test , obstetrics , gestation , endocrinology , type 2 diabetes , insulin resistance , biology , genetics
Aims. To determine sensitivity and specificity of glycated hemoglobin (HbA1c) test with direct immunoturbidimetry as a method to diagnose gestational diabetes (GD). Materials and Methods. 74 pregnant females were recruited during initial screening. Glycemic disorders were diagnosed with two methods: oral glucose tolerance test with 75 g of glucose and glycated hemoglobin test. Results. HbA1c test with direct immunoturbidimetry is a highly sensitive method for diagnosis of glycemic disorders of pregnancy, provided that cut-off level is lowered to 5.5%. Conclusion. Mild anemia was not found to have a significant impact on diagnostic value of HbA1c test.