Vildagliptin: the first innovative DDP-4 inhibitor
Author(s) -
Edvin Villkhauer
Publication year - 2010
Publication title -
diabetes mellitus
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-5499
Subject(s) - vildagliptin , sitagliptin , dipeptidyl peptidase 4 , medicine , pharmacology , dipeptidyl peptidase , dipeptidyl peptidase 4 inhibitor , type 2 diabetes mellitus , saxagliptin , type 2 diabetes , diabetes mellitus , endocrinology , enzyme , biochemistry , chemistry
A review of the main stages of investigation undertaken by Novartis Pharmaceuticals in search of a new molecule for the treatment of type 2 diabetesmellitus, dipeptidyl peptidase-4 (DPP-4) inhibitor (Vildaglyptin). The data on specificity and selectivity of the action of this molecule are presentedalong with the results of its comparison with another agent of this group (sitagliptin).
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