Open AccessInsulin pump therapy of type 1 diabetes mellitus in children and adolescents in the Moscow region
Author(s) -
E E Petryaykina,
Петряйкина Елена Ефимовна,
О. В. Духарева,
Духарева Ольга Викторовна,
И Г Рыбкина,
Рыбкина Ирина Георгиевна,
Е А Пронина,
Пронина Екатерина Александровна,
Tatiana Dmitrievna Mikhaylova,
Михайлова Татьяна Дмитриевна,
Irina V. Garyaeva,
Гаряева Ирина Викторовна,
Eleonora Tavanovna Mandzhieva,
Манджиева Элеонора Тавановна,
И Э Волков,
Волков Игорь Эдуардович,
Natalya Mikhailovna Grenkova,
Гренкова Наталья Михайловна
Publication year - 2009
Publication title -
saharnyj diabet
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.155
H-Index - 12
eISSN - 2072-0378
pISSN - 2072-0351
DOI - 10.14341/2072-0351-5455
Subject(s) - medicine , glycated hemoglobin , insulin , insulin pump , diabetes mellitus , insulin delivery , type 1 diabetes , pediatrics , endocrinology , type 2 diabetes
Aim. To assess dynamics of glycated hemoglobin levels and insulin doses per kg bw in children and adolescents with poorly controlled type 1 diabetes mellitus using insulin pumps. Materials and methods. Retrospective analysis of HbA1c levels and insulin doses per kg bw in children aged 2-17 years with DM1 (mean duration 5.3?3.1) before and 18 months after onset of insulin pump therapy (Medtronic Minimed 712 and 722) with a short-acting insulin analog Novopramid (Novo Nordisk) or Humalog (Ely Lilly) given to 55 (52,4%) and 50 (47,6%) of the patients respectively. НbА1с level and mean daily insulin dose per kg bw were determined when a patient visited the doctors office every 3 months. Results. Insulin pump therapy in patients with initially poorly controlled DM1 resulted in a decrease of HbA1c from 9.8?0.8 to 7,8?0,5% within 18 months after its beginning (p