Open AccessMethods for guantificative assessment of insulin resistance
Author(s) -
Alexander Yur'evich Mayorov,
Katarína Urbanová,
Gagik Radikovich Galstyan
Publication year - 2009
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.154
H-Index - 5
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/2071-8713-5313
Subject(s) - insulin resistance , insulin , clamp , insulin sensitivity , medicine , endocrinology , computer science , clamping , computer vision
The article delineates the definition of concept of insulin resistance as well as the factors that determine tissue insulin sensitivity; defines the conception of «insulin resistance syndrome» (metabolic syndrome), its criteria and diseases that it accompanies. It is pointed that the golden standard for quantitative assessment of insulin action is hyperinsulinemic euglycemic clamp. Different indexes for indirect measurement of insulin resistance and possibilities of use of mathematical models for this matter are discussed.