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Vliyanie perinatal'nykh faktorov na razvitieozhireniya vo vzroslom vozraste
Author(s) -
Alisa V. Vitebskaya
Publication year - 2010
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.154
H-Index - 5
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/2071-8713-5272
Subject(s) - obesity , overweight , medicine , pregnancy , leptin , obstetrics , pediatrics , endocrinology , physiology , environmental health , biology , genetics
The studies of perinatal factors long-term effects on obesity development are summarized in this article. Maternal body massand nutrition role during pregnancy was demonstrated in Dutch hunger studies and several works in vivo. The association between birthweight, obesity, and abdominal fat distribution in future life were demonstrated several times. Breast feeding duration and risk of obesityhave inverse association, but excessive breast feeding also can increase obesity risk. Early accelerated weight gain and further risk of obesityare also associated. Based on the effect of nitrition in preterm newborns study and several works in vivo it is hypothesized that increasedfood consumption during infancy can program elevated leptin concentrations for fat mass ratio durng future life. Further investigationsin this area can lead to breakthrough in solving the problem of obesity and overweight prophylaxis.

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