Open AccessMetabolic syndrome as a prothrombogenic state
Author(s) -
M A Berkovskaya,
С А Бутрова
Publication year - 2009
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/2071-8713-5239
Subject(s) - abdominal obesity , fibrinolysis , metabolic syndrome , hemostasis , obesity , diabetes mellitus , medicine , coagulation , pathogenesis , type 2 diabetes mellitus , bioinformatics , intensive care medicine , endocrinology , biology
The prevalence of obesity has reached epidemic proportions nowadays. Abdominal obesity is the most unfavorable one, because of its association with the complex of markers and risk factors ofcardiovascular diseases and type 2 diabetes mellitus, which is called metabolic syndrome (MS). MS also increases risk of atherothrombosis because it is characterized by low fibrinolysis and prothrombogenic changes in coagulation and platelet hemostasis. The review highlights the mechanisms of hemostatic disturbances in MS, which eхends our scientific knowledge about pathogenesis of cardio vascular diseases