Clinical case: multiple endocrine neoplasia type 1 (MEN 1) | Zendy

A K Lipatenkova | Zendy; Larisa Dzeranova | Zendy; Е А Пигарова | Zendy; Liudmila Rozhinskaya | Zendy; А. В. Кочатков | Zendy

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Clinical case: multiple endocrine neoplasia type 1 (MEN 1)

Author(s) -

A K Lipatenkova,

Larisa Dzeranova,

Е А Пигарова,

Liudmila Rozhinskaya,

А. В. Кочатков

Publication year - 2012

Publication title -

obesity and metabolism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.154

H-Index - 5

eISSN - 2306-5524

pISSN - 2071-8713

DOI - 10.14341/2071-8713-5129

Subject(s) - endocrine system , multiple endocrine neoplasia , men1 , pancreas , endocrinology , medicine , endocrine gland , biology , hormone , genetics , gene

Multiple endocrine neoplasia syndrome type 1 (MEN1, Wermer syndrome) – group o а heterogeneous inherited deseases, caused by hyperlasia or neoplasia of several endocrine glands. The phenotype of MEN1 is broad, and over 20 different combinations of endocrine and non-endocrine metabolic manifestations have been described. This case demonstrates multiple formations of endocrine organs, starting non-classical with macroprolactonoma resistant to dopamine agonists therapy, other endocrine disorders developed gradually eventually: hyperparathyreoidism and hypoglycemia caused by pancreas lesions, produced proinsulin in high levels.

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