Open Access
Prospects for the use of selective estrogen receptor modulator tamoxifen
Author(s) -
Н С Быканова,
Ekaterina Pigarova,
Л. К. Дзеранова
Publication year - 2012
Publication title -
ožirenie i metabolizm
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.154
H-Index - 5
eISSN - 2306-5524
pISSN - 2071-8713
DOI - 10.14341/2071-8713-5049
Subject(s) - tamoxifen , selective estrogen receptor modulator , neuroprotection , medicine , estrogen , estrogen receptor , pregnancy , infertility , antiestrogen , pathological , oncology , endocrinology , bioinformatics , biology , cancer , breast cancer , genetics
The review presents a contemporary data concerning the use of tamoxifen in wide range of pathological conditions: central nervous system diseases and mechanisms of neuroprotective action of estrogen receptors, pituitary tumors with the accent on the treatment of prolactinomas, infertility treatment. We also discuss the risks of tamoxifen treatment for pregnancy induction in women including complications of pregnancy, fetus malformations.