COVID-19 in India: Are Biological and Environmental Factors Helping to Stem the Incidence and Severity?
Author(s) -
Sankha Shubhra Chakrabarti,
Upinder Kaur,
Anindita Banerjee,
Upasana Ganguly,
Tuhina Banerjee,
Sarama Saha,
Gaurav Parashar,
Suvarna Prasad,
Suddhachitta Chakrabarti,
Amit Mittal,
Bimal K. Agrawal,
Ravindra K. Rawal,
Robert Chunhua Zhao,
Indrajeet Singh Gambhir,
Rahul Khanna,
Ashok K. Shetty,
Kunlin Jin,
Sasanka Chakrabarti
Publication year - 2020
Publication title -
aging and disease
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.808
H-Index - 54
ISSN - 2152-5250
DOI - 10.14336/ad.2020.0402
Subject(s) - pandemic , covid-19 , government (linguistics) , medicine , disease , transmission (telecommunications) , environmental health , perspective (graphical) , economic growth , immunology , infectious disease (medical specialty) , linguistics , philosophy , pathology , artificial intelligence , computer science , electrical engineering , engineering , economics
The ongoing Corona virus (COVID-19) pandemic has witnessed global political responses of unimaginable proportions. Many nations have implemented lockdowns that involve mandating citizens not to leave their residences for non-essential work. The Indian government has taken appropriate and commendable steps to curtail the community spread of COVID-19. While this may be extremely beneficial, this perspective discusses the other reasons why COVID-19 may have a lesser impact on India. We analyze the current pattern of SARS-CoV-2 transmission, testing, and mortality in India with an emphasis on the importance of mortality as a marker of the clinical relevance of COVID-19 disease. We also analyze the environmental and biological factors which may lessen the impact of COVID-19 in India. The importance of cross-immunity, innate immune responses, ACE polymorphism, and viral genetic mutations are discussed.
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