
Fecal Microbiota Transplants Annually and Their Positive Clinical Impact
Author(s) -
Lamia Mamoon,
Scott W. Olesen
Publication year - 2020
Publication title -
clinical and translational gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.673
H-Index - 35
ISSN - 2155-384X
DOI - 10.14309/ctg.0000000000000247
Subject(s) - medicine , fecal bacteriotherapy , clostridioides , feces , population , clostridium difficile , environmental health , microbiology and biotechnology , antibiotics , biology
Although fecal microbiota transplantation (FMT) is a recommended, clinically efficacious, and cost-effective treatment for recurrent Clostridioides difficile infection (CDI), the scale of FMT use in the United States is unknown. METHODS: We developed a population-level CDI model. RESULTS: We estimated that 48,000 FMTs could be performed annually, preventing 32,000 CDI recurrences. DISCUSSION: Improving access to FMT could lead to tens of thousands fewer C. difficile episodes per year.