Open AccessSerum Soluble Receptor for AGE (sRAGE) Levels Are Associated With Unhealthy Lifestyle and Nonalcoholic Fatty Liver Disease
Author(s) -
Dana IvancovskyWajcman,
Shira ZelberSagi,
Naomi Fliss Isakov,
Muriel Webb,
Meir Zemel,
Oren Shibolet,
Revital Kariv
Publication year - 2019
Publication title -
clinical and translational gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.673
H-Index - 35
ISSN - 2155-384X
DOI - 10.14309/ctg.0000000000000040
Subject(s) - medicine , nonalcoholic fatty liver disease , odds ratio , insulin resistance , confidence interval , gastroenterology , fatty liver , endocrinology , diabetes mellitus , glycation , obesity , disease , receptor
Nonalcoholic fatty liver disease (NAFLD) has been demonstrated to be positively associated with serum advanced glycation end products (AGEs) and negatively with soluble receptor for AGE (sRAGE) in a few small studies. We aimed to test the association between lifestyle and sRAGE levels and the association between sRAGE levels or AGEs intake and NAFLD, insulin resistance (IR), and elevated alanine aminotransferase (ALT).