Open AccessThyroid Disease–Induced Hepatic Dysfunction: A Clinical Puzzle
Author(s) -
Chimaobi M. Anugwom,
Thomas M. Leventhal
Publication year - 2021
Publication title -
acg case reports journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.112
H-Index - 4
ISSN - 2326-3253
DOI - 10.14309/crj.0000000000000555
Subject(s) - medicine , thyroid dysfunction , hepatic dysfunction , hepatic encephalopathy , coagulopathy , liver disease , disease , liver injury , encephalopathy , thyroid , intensive care medicine , liver failure , liver dysfunction , cirrhosis
The diagnostic evaluation of an individual with clinical and laboratory evidence of thyroid dysfunction in the setting of acute liver injury is crucial. There is a complex relationship between the thyroid and the liver, and so, it requires a careful elucidation of the inciting disease process before instituting a treatment plan. We discuss a patient who had presented with coagulopathy, encephalopathy, and laboratory evidence of acute liver injury, hence adjudged to have developed drug-induced acute liver failure and transferred for liver transplant evaluation. She was found to have liver dysfunction from uncontrolled thyroid disease, with immediate and rapid improvement after controlling severe hyperthyroidism.