Open AccessA Rare Case of Squamous Cell Carcinoma of the Esophagus in a Patient With Goltz Syndrome
Author(s) -
Maida Hafiz,
Suneha Sundaram,
Abdul Rafeh Naqash,
James Speicher,
Ann Sutton,
Paul R. Walker,
Nizar Talaat
Publication year - 2019
Publication title -
acg case reports journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.112
H-Index - 4
ISSN - 2326-3253
DOI - 10.14309/crj.0000000000000045
Subject(s) - medicine , esophagus , dysphagia , papillomatosis , malignant transformation , dermatology , basal cell , carcinoma , pathology , radiology
Esophageal squamous cell carcinoma (ESCC) is the predominant type of esophageal carcinoma worldwide. It occurs mostly in the upper and middle thirds of the esophagus. We present the case of a young African American woman with Goltz syndrome who presented with dysphagia and weight loss and was found to have distal esophageal papillomatosis and squamous cell carcinoma. This occurrence of ESCC in an atypical location in a young woman without traditional risk factors is suggestive of malignant transformation of underlying papillomatosis. Goltz syndrome is a rare disorder, occasionally associated with esophageal papillomatosis. Although esophageal papillomatosis is considered to be benign, our case shows that it could have malignant potential and hence is likely worthy of surveillance.