Open AccessA Safety and Efficacy Comparison of a New Sulfate-Based Tablet Bowel Preparation Versus a PEG and Ascorbate Comparator in Adult Subjects Undergoing Colonoscopy
Author(s) -
Jack A. Di Palma,
Raj Bhandari,
Mark Cleveland,
Daniel S. Mishkin,
Jessica Tesoriero,
Sue Hall,
John McGowan
Publication year - 2020
Publication title -
the american journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.907
H-Index - 252
eISSN - 1572-0241
pISSN - 0002-9270
DOI - 10.14309/ajg.0000000000001020
Subject(s) - medicine , colonoscopy , evening , peg ratio , morning , laxative , gastroenterology , cathartic , colorectal cancer , constipation , physics , finance , cancer , astronomy , economics
A new tablet-based bowel prep for colonoscopy has been developed containing poorly absorbed sulfate salts which act to retain water within the intestinal lumen resulting in a copious diarrhea, thereby cleansing the bowel. This study evaluated the safety and efficacy of these oral sulfate tablets (OST) compared with a US FDA-approved bowel prep solution containing PEG3350, electrolytes, and ascorbate (polyethylene glycol and ascorbate [PEG-EA]).