Open AccessConstipation Predominant Irritable Bowel Syndrome and Functional Constipation Are Not Discrete Disorders: A Machine Learning Approach
Author(s) -
James K. Ruffle,
Linda Tinkler,
Christopher Emmett,
Alexander C Ford,
Parashkev Nachev,
Qasim Aziz,
Adam D. Farmer,
Yan Yiannakou
Publication year - 2020
Publication title -
the american journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.907
H-Index - 252
eISSN - 1572-0241
pISSN - 0002-9270
DOI - 10.14309/ajg.0000000000000816
Subject(s) - medicine , irritable bowel syndrome , constipation , abdominal pain , functional constipation , cohort , quality of life (healthcare) , gastroenterology , physical therapy , nursing
Chronic constipation is classified into 2 main syndromes, irritable bowel syndrome with constipation (IBS-C) and functional constipation (FC), on the assumption that they differ along multiple clinical characteristics and are plausibly of distinct pathophysiology. Our aim was to test this assumption by applying machine learning to a large prospective cohort of comprehensively phenotyped patients with constipation.