Open AccessIndependent Blinded Validation of a Tissue Systems Pathology Test to Predict Progression in Patients With Barrett's Esophagus
Author(s) -
Jon M. Davison,
John R. Goldblum,
Udhayvir Singh Grewal,
Kevin McGrath,
Kenneth E. Fasanella,
Christopher Deitrick,
Aaron D. DeWard,
Emily A. Bossart,
Stephen L. Hayward,
Yi Zhang,
Rebecca J. Critchley-Thorne,
Prashanthi N. Thota
Publication year - 2020
Publication title -
the american journal of gastroenterology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.907
H-Index - 252
eISSN - 1572-0241
pISSN - 0002-9270
DOI - 10.14309/ajg.0000000000000556
Subject(s) - medicine , dysplasia , barrett's esophagus , hiatal hernia , esophagus , confidence interval , gastroenterology , predictive value of tests , risk assessment , adenocarcinoma , disease , cancer , reflux , computer security , computer science
A risk prediction test was previously validated to predict progression to high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus (BE). The aim of our study was to independently validate this test to predict the risk of progression to HGD/EAC in BE patients with nondysplastic (ND), indefinite for dysplasia and low-grade dysplasia (LGD).