Open AccessPrognostic Implication of Stress Induced Hyperglycemia in Non Diabetic Patients with Acute Coronary Syndrome
Author(s) -
Sanjay Tukaram Thorat,
Radhika Bajaj,
Vaibhav Vijay Rane,
Avanti Jayant Damle,
Nikhil Dilip Patil,
Pankaj Pawar
Publication year - 2021
Publication title -
journal of evolution of medical and dental sciences
Language(s) - English
Resource type - Journals
eISSN - 2278-4802
pISSN - 2278-4748
DOI - 10.14260/jemds/2021/794
Subject(s) - medicine , stress hyperglycemia , acute coronary syndrome , diabetes mellitus , blood sugar , unstable angina , group b , heart failure , angina , cardiology , myocardial infarction , insulin , endocrinology
BACKGROUND Hyperglycemia is a common finding during the admission of non-diabetic patients with acute coronary syndrome. It is very essential to differentiate this stress hyperglycemia from the hyperglycemia in latent diabetics whose diabetes may have been unmasked by the stress of acute coronary syndrome (ACS). We conducted this study to evaluate stress hyperglycemia in non-diabetic patients with ACS. METHODS We conducted this cross sectional study in the Department of Medicine, KIMS Hospital, Karad, over a period of one year. Non-diabetic patients with HbA1c 0.05) We had 47 cases of unstable angina (UA – 47%) followed by 43 cases of STEMI (43 %) and 10 cases of NSTEMI (10 %). We observed a significant difference in the presence of complications in the two groups (p<0.001), Group B patients with hyperglycemia had more complications. Significant difference was seen between the presence of heart failure, arrhythmias and shock in the two groups, with group B having more incidences of these (p<0.05). Significant difference in the outcome of the two groups was seen (p = 0.012). We observed that out of 38 patients in Group B with hyperglycemia, there were 8 deaths (21.05%) as compared to 3 deaths (4.84%) in Group A patients. CONCLUSIONS We observed that the high prevalence (38%) of stress in non-diabetic ACS patients is responsible for significantly more complications, more chances of heart failure, arrhythmia, shock and more deaths. KEY WORDS Acute Coronary Syndrome, Stress Hyperglycemia, Non-Diabetic Patients, Outcome