A Study of Relationship of Bone Mineral Density with Age, Body Mass Index, Obesity and Serum Magnesium Level

BACKGROUND Menopause is defined as the permanent cessation of menstruation following loss of ovarian activity. One of the most important problems associated with menopause is osteoporosis. This study was conducted to evaluate the relationship between bone mineral density, body mass index, age, serum calcium, and serum magnesium in 120 women. METHODS Present study was an observational study done from Feb 2017 to July 2017 in Pt. J.N.M. Medical College to evaluate the relationship of bone mineral density with age, body mass index (BMI), obesity and serum magnesium in 120 postmenopausal women. A detailed medical, obstetrical, menstrual, and drug history was recorded in a proforma designed for the study. Past fracture history, family history of fracture and osteoporosis, socioeconomic status, occupation, educational level and weightbearing exercises were collected and recorded. RESULTS Average age of women with normal bone health was 30.5 + 0.58 years, while the age of osteopenic and osteoporotic women was 43.11 + 6.79 years and 54.64 + 11.92 years respectively. Most of the osteopenic women belonged to the age group of 40 – 49 years. Osteoporotic patients (78.57 %) had a high (> 0.85) waist-hip ratio, while women with normal bone mineral density had a normal waist-hip ratio. Most of the women with normal bone mineral density (100 %), osteopenia (85.29 %) and osteoporosis (57.14 %) had normal serum magnesium levels. CONCLUSIONS We found that the bone mineral density reduced with advancing age, decreasing BMI and obesity, while we found no correlation of serum magnesium level with bone mineral density (BMD). KEY WORDS Bone Mineral Density, Body Mass Index, Perimenopause, Magnesium, Calcium