Open AccessComparative Evaluation of the Antimicrobial Efficacy of Different Irrigating Solutions on Endodontic Pathogens - An In Vivo Study
Author(s) -
Suneeth Shetty,
Sunil Tejaswi,
U K Ambikathanya,
Akanksha Mittal
Publication year - 2021
Publication title -
journal of evolution of medical and dental sciences
Language(s) - English
Resource type - Journals
eISSN - 2278-4802
pISSN - 2278-4748
DOI - 10.14260/jemds/2021/169
Subject(s) - sodium hypochlorite , medicine , azadirachta , enterococcus faecalis , dentistry , antimicrobial , pulpectomy , endodontic therapy , agar diffusion test , root canal , traditional medicine , microbiology and biotechnology , antibacterial activity , chemistry , biology , bacteria , organic chemistry , genetics , staphylococcus aureus
BACKGROUND The key to a successful endodontic treatment is to ensure complete eradication of the infection present and to prevent reinfection. This depends on meticulous disinfection using intracanal irrigants. In dentistry the most commonly used irrigant is sodium hypochlorite which has the disadvantages of cytotoxicity and unpleasant taste. The extracts of neem have been used since ages for their medicinal values and used widely for health care. However, the potential use of such an agent for the success of endodontic procedures has not yet been investigated. Hence, if proved effective, such a natural agent will have a dominant hold against the chemical disinfectants in terms of biocompatibility and tissue response. This study aimed to evaluate the effectiveness of Q-MIX (2 in 1), 10 % neem (Azadirachta indica), and 2 % sodium hypochlorite on the growth and culture of Enterococcus faecalis and Mutant Streptococcus over a period of 4 weeks. METHODS This is a descriptive study conducted among samples collected from 30 healthy patients who were indicated for pulpectomy. The sample size was taken for convenience. Incisors of these individuals were selected on the basis that they had to undergo endodontic treatment due to primary endodontic infection. The zones of inhibition were measured by agar well diffusion method. Statistical analysis was done using independent T test & chi-square test. RESULTS Statistical analysis showed that the mean zones of inhibition in this study were 20.54 mm, 9.65 mm and 4.54 mm for Q-MIX (2 in 1), 10 % neem and 2 % sodium hypochlorite. The significance was greater between Q-MIX (2 in 1) and the other two agents as the P-value was < 0.001. CONCLUSIONS The result indicated Q-MIX (2 in 1) is a more effective root canal irrigant when compared to 10 % neem and 2 % sodium hypochlorite. KEY WORDS Q-MIX (2 in 1), Azadirachta indica, Apical Periodontitis, Enterococcus faecalis