Open AccessD+ hemolytic uremic syndrome
Author(s) -
Ni Made Sumiartini,
I Nyoman Lila,
I Ketut Suarta
Publication year - 2016
Publication title -
paediatrica indonesiana
Language(s) - English
Resource type - Journals
eISSN - 2338-476X
pISSN - 0030-9311
DOI - 10.14238/pi44.2.2004.80-4
Subject(s) - medicine , thrombotic microangiopathy , enteritis , pathogenesis , hemolytic anemia , microangiopathy , anemia , immunology , gastroenterology , disease , endocrinology , diabetes mellitus
Hemolytic uremic syndrome (HUS) is characterized by anemia microangiopathy, thrombocytopenia, and acute renalfailure, predominantly occurs in childrenyounger than 4 years of age. It is the most commoncause of acute renal failure in children.1,2 HUS is dividedinto two categories, the epidemic type which isaccompanied by enteritis (D+HUS) and the sporadictype which is not accompanied by enteritis (D-HUS).The pathogenesis is unknown, but available evidencestrongly suggests endothelial cell damage in the organs.