Open AccessAn Efficient and One Pot Synthesis of 2,4,5-Trisubstituted Imidazole Derivatives Catalyzed by Silver Nanoparticles
Author(s) -
S.M. Bagwan,
Mohamad Asif
Publication year - 2022
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2022.23589
Subject(s) - benzil , chemistry , imidazole , catalysis , benzoin , yield (engineering) , ammonium acetate , silver nanoparticle , one pot synthesis , nanoparticle , solvent , ammonium persulfate , organic chemistry , combinatorial chemistry , nuclear chemistry , nanotechnology , materials science , high performance liquid chromatography , polymer , metallurgy , polymerization
Silver nanoparticles (AgNPs) have been used as an excellent and highly efficient catalyst for one potsynthesis of 2,4,5-trisubstituted imidazole derivatives in presence of ethanol as a solvent. This syntheticroute involves multicomponent reaction of benzil, substituted aromatic aldehydes and ammoniumacetate under reflux. The synthesized silver nanoparticles were characterized by UV-visible spectroscopy(UV-visible), X-ray diffraction (XRD) pattern, scanning electronic microscope (SEM) analysis. Theprocess was simple and environmentally benign with high to excellent yield. The methods providesseveral advantages such as simple operation, clean reaction profile, short reaction time and high yieldof product. The synthesized silver nanoparticles as catalyst was non-toxic, eco-friendly, low cost andgreen synthetic method.