Open AccessFabrication of Minerals Substituted Hydroxyapatite based Nanocomposite Coating on Titanium: Physico-Chemical and in vitro Biological Evaluations
Author(s) -
Dharman Govindaraj,
Mariappan Rajan
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2022.23441
Subject(s) - nanocomposite , coating , titanium , halloysite , electrophoretic deposition , chemical engineering , chemistry , carbon nanotube , fourier transform infrared spectroscopy , gelatin , substrate (aquarium) , materials science , nanotechnology , composite material , organic chemistry , oceanography , geology , engineering
The search of orthopedic metallic implants which facilitate osteoconductivity and mitigate bacterialcontamination has received substantial care to ensure long-term problems in the biomedical sector.Current research studies electrophoretic deposition of gelatin (Gel)@minerals (Ce, Mg, Zn) substitutedhydroxyapatite (MHA2)-halloysite nanotube (HNT)-single-walled carbon nanotubes (SWCNT)(Gel@MHA2-HNT-SWCNT) nanocomposite coatings on the surface of titanium plate. Coated sampleswere characterized by FTIR, XRD and SEM-EDX techniques. Furthermore, antimicrobial, hemolysisand cell viability studies of coating materials and their findings show the bacteriostatic activity,hemocompatibility and more viable cells, respectively. Overall, the in vitro experiments have shownthat Gel@MHA2-HNT-SWCNT nanocomposite coating on titanium enhanced the biocompatibleefficiency, suggesting that Gel@MHA2-HNT-SWCNT coated titanium is a potential implant substratefor orthopedic implants.