Open AccessAlginate and Gum Arabic Coated Iron Oxide Nanoparticles as an Efficient Drug Carrier Agent
Author(s) -
Jaiveer Singh,
Arti Jangra,
K. Manjula Rani,
Parvin Kumar,
Suresh Kumar,
Ramesh Kumar
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2022.23421
Subject(s) - surface modification , iron oxide nanoparticles , thermogravimetric analysis , nanoparticle , magnetite , iron oxide , chemistry , coating , chemical engineering , fourier transform infrared spectroscopy , nanotechnology , magnetite nanoparticles , oxide , magnetic nanoparticles , nuclear chemistry , materials science , organic chemistry , metallurgy , engineering
Multifunctional iron oxide nanoparticles have a vast and emerging scope in the field of nanotechnology.Out of numerous techniques available to develop multifunctional magnetite nanoparticles,co-precipitation is considered as one of the most efficient and economical techniques. Bare magnetitenanoparticles could be functionalized to act as multifunctional nanoparticles with the help of somesuitable and biocompatible coating materials. In present study, surface functionalization of magneticiron oxide nanoparticles has been carried out with alginate and gum Arabic, respectively. For theconfirmation of surface functionalization, the synthesized multifunctional magnetite nanoparticleswere characterized FTIR spectroscopy and thermogravimetric analysis. Further, the drug loadingefficiency of these surface coated iron oxide nanoparticles has been evaluated with the help of UV-visiblespectrophotometric studies