Open AccessFrom Biowaste to Biomaterials: Buffalo Teeth Derived Hydroxyapatite Based Biocomposites for Bone Tissue Applications
Author(s) -
K. Manivannan,
G. Jaganathan,
Mohamed Aboobucker Sithique
Publication year - 2022
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2022.23270
Subject(s) - biocomposite , biopolymer , aloe vera , chitosan , antimicrobial , chemistry , fourier transform infrared spectroscopy , coating , materials science , chemical engineering , nuclear chemistry , food science , composite material , composite number , polymer , organic chemistry , microbiology and biotechnology , biology , engineering
The present study reported the preparation of food industry biowaste buffalo teeth-derivedhydroxyapatite (BT-HA)/chitosan-polyvinyl pyrrolidone (CS-PVP)/aloe vera (ALV) natural biopolymeras a biocomposite for improved mechanical, antimicrobial and cytocompatible characteristics. Thestrengthening of biopolymer has a major role to play in improving the mechanical properties of thebiocomposite, while the addition of aloe vera increases antimicrobial and cytocompatibility. Chemicalstructure, crystalline phase, morphology and mechanical property biocomposite were studied by FTIR,XRD, SEM-EDX and micro-hardness tests, respectively. Additionally, the antimicrobial effectivenessof the biocomposites was evaluated using Gram-positive and Gram-negative bacteria. Thecytocompatibility of osteoblast cells to the biocomposites was calculated by the MTT assay examination.The findings demonstrated that the prepared biocomposite has the necessary mechanical, antimicrobialand biocompatible characteristics. Generally, the mixture of mechanical characteristics of CS-PVP,the antimicrobial and cytocompatible property of aloe vera in BT-HA/CS-PVP/ALV, makes thebiocomposite a prospective restorative substance for various clinical applications.