Open AccessBioactive Metal Complexes of Schiff Base Derived from 2,3-Dioxobutane, Ethane-1,2-diamine and 4-Chloro-2-formylphenol: Spectral Studies and in vitro Antimicrobial Activity
Author(s) -
Abhay Nanda Srivastva,
Sayanwita Panja,
Netra Pal Singh,
Chandra Kiran Shriwastaw
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23478
Subject(s) - chemistry , ligand (biochemistry) , schiff base , molar conductivity , carbon 13 nmr , metal , cobalt , proton nmr , metal ions in aqueous solution , diamine , magnetic moment , inorganic chemistry , medicinal chemistry , crystallography , stereochemistry , polymer chemistry , organic chemistry , biochemistry , receptor , physics , condensed matter physics
A novel series of trivalent coordination complexes was synthesized by the reaction between a chloride/acetate salt of iron, chromium, cobalt or manganese ions and NNNNOO type persuasive Schiff baseligand synthesized from 2,3-dioxobutane, ethane-1,2-diamine and 4-chloro-2-formylphenol.Synthesized compounds were characterized by using elemental analysis, molar conductance, magneticmoment, IR, UV-visible, 1H NMR, 13C NMR and ESI-MS spectral analyses. IR and NMR spectrafavoured hexadentate coordination behaviour of ligand. Electronic spectra and magnetic moment datareveal Oh geometry with distortion around the metal ion in complexes. The molar conductance valuesshow 1:1 electrolytic nature of complexes. Biological potentiality of the ligand and its metal complexeswere tested in vitro against two bacterial and two fungal strains; Bacillus subtilis, Escherichia coli andAspirgillus niger, Aspirgillus flavus, respectively.