Open AccessSynthesis, Characterization and Antimicrobial Screening of Some Organotin Complexes Derived from Salicyl Hydrazide Schiff Bases
Author(s) -
. Priyanka,
Hardeep Singh Tuli,
Pallvi Aggarwal,
Manoj Kumar
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23429
Subject(s) - chemistry , hydrazide , dehydroacetic acid , carbon 13 nmr , antimicrobial , hydrate , proton nmr , elemental analysis , mass spectrometry , organic chemistry , nuclear chemistry , medicinal chemistry , chromatography
A series of new organotin(IV) compounds [Me2SnL], [Et2SnL], [Bu2SnL] and [Ph2SnL], where L =2-hydroxy-N-(1-(4-hydroxy-6-methyl-2-oxo-2H-pyran-3-yl)ethylidene)benzohydrazide has beensynthesized by refluxing methyl salicylate hydrazide hydrate with dehydroacetic acid (DHA) with thecorresponding organotin(IV) chlorides. All the compounds were characterized by elemental analyses,FT-IR, 1H NMR, 13C NMR, 119Sn NMR and mass spectrometry. The synthesized complexes found tohave wide therapeutic potential.