Open AccessReview on Synthesis Route of Quinazoline Based Hybrid Derivatives
Author(s) -
Pravin Deharkar,
Shridhar Satpute,
Deepa Panhekar
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23373
Subject(s) - quinazoline , antifungal , chemistry , biochemical engineering , combinatorial chemistry , nanotechnology , computer science , engineering , medicine , materials science , dermatology
Quinazolines are amidst the most significant pharmacological compounds in natural and medicinalchemistry, with a wide variety of pharmacological things, including antifungal, antibacterial,anti-inflammatory, anti-HIV, anticancer and analgesic activity. Designing innovative quinazolines,studying possible techniques to synthesize quinazolines, examining diverse features of quinazolinesand looking for prospective uses of quinazolines have all become more important in the last twodecades due to their multiple possible applications. The current review paper discusses the synthesisof quinazolines using the multi-component synthetic technique that is environmentally friendly, mildand atom-efficient. The discussion is separated into sections based on the key processes used to constructquinazoline scaffolds to provide an efficient approach for a more significant grasp. The most recentreferences have also been taken into account. The review should prove useful in future research onquinazoline synthesis and developing a more promising synthetic technique.