Open AccessGC-MS Analysis, Phytochemical Screening and Biological Activity of Bauhinia tomentosa (Linn.)
Author(s) -
Raffaella Mini,
Varun V. Prabhu,
K. Vimaladevi,
J. Sowmiya,
G Sibi
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23363
Subject(s) - phytochemical , chemistry , phytol , squalene , terpenoid , traditional medicine , glycoside , terpene , antibacterial activity , astringent , food science , stereochemistry , organic chemistry , biochemistry , bacteria , biology , medicine , taste , genetics
Present study aimed to evaluate the chemical composition and biological activity for methanolic extractof Bauhinia tomentosa (Linn.) leaves grown in Western Ghats region of South India. The preliminaryphytochemical screening tests revealed the presence of steroids, alkaloids, terpenoids, flavonoids,glycosides and phenolic compounds in the leaf extract. A total of 19 compounds were identifiedthrough gas chromatography-mass spectroscopy (GC-MS) analysis of methanolic extract of B.tomentosa. The major compounds identified were phytol (23.96%), n-hexadecanoic acid (11.62%),squalene (8.85%) and the minor compounds are trans-bis(2-methylpropyl)-4,6-dioxane(0.13%),dihydro-cis-α-copaene-8-ol (0.14%), tetradecanoic acid (0.81%), respectively. Antibacterial activityof the extract showed the zone of inhibition 18 mm at 200 μg/mL against S. aureus, followed by 15 and16 mm against S. anginosus, K. pneumoniae at 200 μg/mL, respectively. Antioxidant activity ofmethanolic extract of B. tomentosa leaves showed the maximum IC50 value with 75.07 % of scavengingactivity at the concentration of 5 μg/mL.