Open AccessSynthesis of New Class of Functionalized Flavones/Isoxazole Derivatives-Nitrile oxide 1,3-Dipolar Cycloaddition
Author(s) -
Neeradi Balaiah,
Y. Hemasri
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23360
Subject(s) - isoxazole , chemistry , nitrile , cycloaddition , 1,3 dipolar cycloaddition , flavones , proton nmr , carbon 13 nmr , alkyne , oxide , organic chemistry , combinatorial chemistry , catalysis , chromatography
A new series of functionalized flavone-isoxazole derivatives have been synthesized from alkyne tethered3-hydroxy flavone by adopting facile synthetic method, intermolecular nitrile oxide 1,3-dipolarcycloaddition in the presence of eco-friendly sodium hypochloride oxidant under mild reactionconditions. Structures of all the synthesized compounds were established on the basis of 1H NMR, 13CNMR and ESI-mass.