Open AccessKinetic and Mechanistic Studies of Acidic Hydrolysis of Goniothalamin
Author(s) -
R.P.T. Kim,
M. Niyaz Khan,
Sook Yee Liew,
Khalijah Awang
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23158
Subject(s) - chemistry , hydrolysis , hydrochloric acid , kinetic energy , reaction rate constant , dehydration , ring (chemistry) , kinetics , chemical stability , proton nmr , inorganic chemistry , organic chemistry , biochemistry , physics , quantum mechanics
The acidic hydrolysis of goniothalamin was studied on the spectrophotometric kinetic study at differentconcentration of hydrochloric acid and temperature to determine the stability of the compound. Stabilitytests were performed using UV-VIS detection. This is a two-step reaction that involves formation ofintermediate product. Rate constant of reactant forming intermediate product obeyed pseudo-first-orderkinetic, while the second step to form final product is independent on the concentration of HCl. Thestructure of final products was identified by NMR and MS. The acidic hydrolysis pathway was proposedto involve the opening of lactone ring, followed by dehydration and formation of a double bond.