Open AccessAn Indian Folkore Phytomedicine Perilla frutescens L.: Free Radical Scavenging Property along with Metal Detection by ICP-MS
Author(s) -
Ajay Singh,
Ashwini Kumar Dixit,
Sumaya Farooq,
Zafar Mehmood,
Suman Lata Chhimwal
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23155
Subject(s) - perilla frutescens , chemistry , dpph , phytomedicine , antioxidant , phytochemical , ascorbic acid , polyphenol , perilla , food science , traditional medicine , botany , organic chemistry , biochemistry , biology , medicine , raw material
In present study, free radical scavenging activity of methanolic extract of all parts (leaves, seeds, root,stem and flower) of Perilla frutescens L. has been estimated. The promising results, among the fiveplant parts leaves, seeds, root, stem, flower and the standard tested for the in vitro antioxidant activityusing the DPPH method, the crude methanolic extracts of all parts showed antioxidant activity, withIC50 values of 5.95 ± 0.10, 8.28 ± 0.20, 66.27 ± 0.17, 80.03 ± 0.10 and 122.35 ± 0.17 μg/mL, respectively.The IC50 value for ascorbic acid was 5.19 ± 0.26 μg/mL. While butylated hydroxyl toluene (BHT) asynthetic commercial antioxidant has comparatively high IC50 value of 108.46 ± 0.57 μg/mL. Presenceof zinc in all parts of plant in the range 17.20 ± 0.22 to 33.56 ± 0.32 ppm further supports the strongantioxidant activity of Perilla frutescens L. The phytochemical tests indicated that all parts of Perillafrutescens L. have considerable proportion of important phytochemicals and are in rich source ofsecondary metabolites like polyphenols, tannins, alkaloids and flavonoids. Several of such compoundsare known to possess potent antioxidant activity.