Open AccessGC-MS Chemical Constituents and in vitro Activities of the Oil Extract of Euryops brevipapposus Leaves used Traditionally for the Management of Some Diseases
Author(s) -
Abiodun Atinuke Adegborioye,
Oyinlola Oluwunmi Olaokun,
Benson Chuks Iweriebor,
Larry Chikwulu
Publication year - 2021
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.23066
Subject(s) - dpph , chemistry , antioxidant , traditional medicine , antibacterial activity , asteraceae , essential oil , gas chromatography–mass spectrometry , food science , botany , chromatography , organic chemistry , bacteria , biology , mass spectrometry , medicine , genetics
Euryops brevipapposus (Asteraceae) is a medicinal plant of a local community utilized traditionallyfor its recognized effectiveness in managing non-communicable diseases, especially asthma. Thetraditional use of E. brevipapposus lacks scientific evidence and the increased burden of asthma makesconfirming this claim paramount. The study characterized by GC-MS the bioactive compounds of E.brevipapposus essential oil (EbO) extracted with Clevenger apparatus. The antibacterial efficacy andantioxidant activity by free radical scavenging ability were investigated in vitro using standard methods.A strong antioxidant IC50 value of 6.71 × 10-7 mg/mL of oil was obtained for DPPH. The antibacterialactivity against Escherichia coli and Vibrio spp. (MIC value of 0.055 mg/mL) was superior. GC-MSanalysis of EbO showed α-phellandrene, α-pinene, germacrene D, β-pinene, β-mycrene, (E)-β-ocimeneand bicyclogermacrene as the major compounds. The antioxidant and antibacterial potentials of E.brevipapposus may justify the therapeutic claims and local usage of this plant.