Open AccessSynthesis and Characterization of Novel Analogues of Lopinavir
Author(s) -
Peketi Rajesh Reddy,
Sivanadh Musunuri,
D. Ramasekhara Reddy,
V. Subrahmanyam Chittala,
P. V. N. Murthy,
K. Krishnamohan
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2021.22954
Subject(s) - lopinavir , chemistry , isoleucine , stereochemistry , amino acid , biochemistry , leucine , virology , medicine , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy
The present work describes the identification, origin, synthesis, characterization and control of fournovel analogues of lopinavir viz. leucine analogue of lopinavir, isoleucine analogue of lopinavir, methylanalogue of lopinavir and dihydroxy analogue of lopinavir.