Open AccessChemometric Profile of Calotropis gigantea and its Antioxidant Activity through Bioactive Compounds from Latex, Leaves and Flower Extracts
Author(s) -
Varun V. Prabhu,
V Manjula,
K. Santhiya,
G.P. Tamileela Kanali,
P. Saravanakumar,
G Sibi
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22875
Subject(s) - gigantea , chemistry , abts , dpph , antioxidant , botany , chemotype , gallic acid , traditional medicine , food science , organic chemistry , biology , essential oil , medicine
In present study, antioxidant effect was compared among latex, leaf and flower extract of Calotropisgigantea and is first report on comparing the chemometric profiling of various parts of C. gigantea.Ethanol and chloroform extracts of C. gigantea revealed the presence of 28 different chemotypes inlatex, 27 in leaves and 32 in flowers. Major phtyochemicals present were of which fatty acid ethylesters, fatty alcohols, terpenes, coumarins and carbocycles. C. gigantea leaf extract recorded 78% of2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity and IC50 values of 14.44, 6.74 and 21.35μg/mL were observed for latex, leaves and flower extracts respectively. For 2,2′-azinobis-(3-ethylbenzthiazolin-6-sulfonic acid) [ABTS+] assay, IC50 values ranged between 6.74 and 21.25 μg/mLby various components of C. gigantea. The results represent free radical-scavenging activities ofextracts of several parts of C. gigantea. The findings will definitely use in new directions inpharmacological and therapeutic investigations on C. gigantea latex, leaves and flowers.