Open AccessSynthesis, Characterization of Metal Complexes of Schiff Base derived from Pyrrole-2-carbaldehyde and 4-Methoxy Aniline and their Biological Studies
Author(s) -
Alasdair Charles,
R. Krishnaveni,
K. Sivara
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22874
Subject(s) - chemistry , schiff base , aniline , metal , aspergillus flavus , escherichia coli , methylene , antibacterial activity , nuclear chemistry , pyrrole , aspergillus niger , polymer chemistry , stereochemistry , medicinal chemistry , organic chemistry , bacteria , biochemistry , genetics , food science , biology , gene
The metal complexes of Fe(II), Co(II) and Ni(II) have been synthesized from N-((1H-pyrrol-2-yl)methylene)-4-methoxyaniline. The synthesized Schiff base and its metal complexes were structurallycharacterized based on IR, NMR, UV-vis spectroscopic techniques. The presence of coordinated watermolecules were confirmed by thermal studies. All the synthesized compounds were screened for theirantibacterial (Escherichia coli, Bacillus substilis, Salmonella typhi, Staphylococcus epidermis) andantifungal (Aspergillus flavus) and DNA cleavage activity.