Open AccessAssessment of Murraya koenigii Leaf Extract against New Multiple Drug Resistance Human Enteric Pathogens
Author(s) -
Rudrangshu Chatterjee,
Dushyant Singh,
Manjeet Aggarwal,
Ajit Varma,
Abhishek Chauhan,
Swati Tripathi
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22869
Subject(s) - murraya , pathogenic bacteria , enteric bacteria , antibiotics , antibiotic resistance , drug resistance , human pathogen , microbiology and biotechnology , bacteria , biology , multiple drug resistance , sewage , traditional medicine , medicine , escherichia coli , gene , biochemistry , genetics , waste management , engineering
Sewage waters are the primary habitats to harbour antibiotic resistance bacteria (ARB) especiallymulti-drug resistance (MDR) human enteric pathogens. Microorganisms acquire resistance towardsmany commercial antibiotics due to their inappropriate use. In this study, human enteric pathogenswere isolated, identified and characterized and shows the resistance against five different clinicallysignificant commonly prescribed antibiotics. The bacterial strains were isolated from different sewagetreatment plants located in Delhi city, India. Samples were analyzed for the detection of pathogenichuman enteric bacteria through morphological, biochemical and molecular analysis. Methanolic leafextract of Murraya koenigii showed the significant antibacterial activity against multi drug resistanthuman enteric pathogens. Thus, Murraya koenigii leaves would be a potential alterantive to antibioticregimens for the prevention of gastrointestinal infections.