Open AccessEffect of Heavy Metals on the Andrographolide Content, Phytochemicals and Antioxidant Activity of Andrographis paniculata
Author(s) -
Anna Antony,
Praveen Nagella
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22831
Subject(s) - andrographolide , andrographis paniculata , chemistry , acanthaceae , antioxidant , flavonoid , heavy metals , traditional medicine , food science , botany , environmental chemistry , biochemistry , biology , medicine , alternative medicine , pathology
Andrographis paniculata is a medicinal plant that has several medicinal properties and has been traditionally used in different medicinal preparations. The present study deals with the influence of heavy metals (lead, mercury and silver) on andrographolide, phytochemicals and antioxidant activity in Andrographis paniculata. Two months old saplings were subjected to heavy metal stress of two different concentrations (0.2 mM and 0.4 mM) for three different times at 3 day time interval. The results showed that the saplings treated with heavy metals showed increased concentration of andrographolide content. The saplings treated with 0.4 mM silver showed the highest increase in the andrographolide content (24.58 ± 2.85 mg/g of DW) compared with control (9.41 ± 1.26 mg/g of DW) and other treatments. Variations in the biochemical parameters like total phenolic content, total flavonoid content, etc. were also prominent with all the treated samples when compared to that of control.