Open AccessPhytochemical Compounds and Antibacterial Inhibition Activity of Gel of Aloe vera L. var. chinensis Haw. Berg. of Vietnam
Author(s) -
Do Thi Viet Huong,
Trieu Anh Trung
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22706
Subject(s) - aloe vera , chemistry , traditional medicine , phytochemical , kaempferol , antibacterial activity , emodin , bacteria , flavonoid , chromatography , biochemistry , antioxidant , biology , medicine , genetics
In present study, eight compounds were isolated from the Aloe vera L. var. chinensis Haw. Berg.grown in Vietnam from the methanolic extract. The isolated compounds were elucidated for theirstructures on the basis of NMR spectroscopic data and found to aloe emodin, emodin, 2-hydroxy-1-methoxy-anthraquinone, 1,6-dihydroxy-2-methylanthraquinone, kaempferol 3-O-α-Larabinofuranoside,kaempferol 3-O-gentibioside, β-amyrin and ursolic acid. Antibacterial activity ofAloe vera gel extract showed strong effects on Gram-positive bacteria than Gram-negative stains,except Escherichia coli. At low concentration 50 μg/mL, the crude extract did not showed the inhibition.Four of the five Gram-positive bacteria were inhibited at 100 μg/mL of methanol extract. At 400μg/mL, the maximum zone of inhibition was observed against Bacilluss pumilus (17 mm), Escherichiacoli (15 mm), Sarcina lurtea (13 mm) and Vibrio cholera (12 mm).