Open AccessPreparation of Salicylic Nitrile through Direct Catalytic Dehydration of Salicylamide with Immobilized Phosphoric Acid as Catalyst
Author(s) -
Shu-Feng Yao,
Zhaosheng Cai,
Xujuan Huang,
Lan-Xuan Song
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22545
Subject(s) - salicylamide , chemistry , nitrile , catalysis , phosphoric acid , dehydration , salicylic acid , organic chemistry , nuclear chemistry , biochemistry
Salicylic nitrile was prepared through direct catalytic dehydration of salicylamide under hightemperature using immobilized phosphoric acid as catalyst. The catalytic performances of differentcatalysts were evaluated according to the analytic results of GC-MS, and the feasibility about thepreparation of salicylic nitrile by direct catalytic dehydration of salicylamide was investigated accordingto the composition of product determinated by GC analysis (area nomalization). Experimental resultsindicated the comprehensive property of silica gel supported phosphoric acid was the best one amongall of the catalysts utilized in this study. When the temperature of catalyst bed was 480 ± 10º and silicagel supported phosphoric acid was utilized as catalyst, the conversion ratio of salicylamide was 88.79%,the selectivity to salicylic nitrile was 97.97% and the yields of salicylic nitrile could up to 86.99%.Meanwhile, the experimental results showed the increase of temperature of catalyst bed could resultin the increase of the conversation of salicylamide, but much more by-product could be formed whenthe temperature of catalyst bed was too high.