Open AccessSynthesis of Chiral Melatonin Salts of Dithiophosphoric Acids Using Monoterpenyl Alcohol
Author(s) -
И. С. Низамов,
Ramazan Z. Salikhov,
I. S. Nizamov,
Yevgeniy N. Nikitin,
G. G. Sergeenko,
R. R. Davletshin,
Marina P. Shulaeva,
О. К. Поздеев,
Э. С. Батыева,
Р. А. Черкасов
Publication year - 2020
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2020.22509
Subject(s) - chemistry , borneol , alcohol , melatonin , substituent , indole test , menthol , organic chemistry , medicinal chemistry , stereochemistry , traditional chinese medicine , medicine , alternative medicine , pathology
Dithiophosphoric acids in the terms of (S)-(–)-menthol, (1S)-endo-(–)-borneol,(1R)-endo-(+)-fenchylalcohol and (1S,2S,3S,5R)-(+)-isopinocampheol react with melatonin to form chiral N-acetyl5-methoxytryptammonium dithiophosphates. The interations proceed via increase in the coordinationof indole nitrogen of melatonin. The antibacterial and antifungal activity of N-acetyl5-methoxytryptammonium dithiophosphate containing (+)-fenchyl substituent was established