Open AccessAntimicrobial Activity of Cu(II) and Fe(III) with Pyridine Complexes as Ligands Contrary to Clinical Strains of Bacteria and Fungi Species
Author(s) -
Faridul Islam,
Jannat Al Foisal,
Mahbubur Rahman,
Zahidul Islam,
Mst. Afsana Mimi,
Rasel Habib,
Md. Amran Hossain,
Likson Chowdhury,
Sreebash Chandra Bhattacharjee,
Daxiang Cui
Publication year - 2019
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2019.22096
Subject(s) - chemistry , pyridine , denticity , antimicrobial , molar conductivity , bacteria , nuclear chemistry , alternaria alternata , medicinal chemistry , organic chemistry , metal , botany , biology , genetics
In this study, green coloured Cu(II) and red coloured Fe(III) complexes of pyridine were prepared and the elemental characterization confirmed their composition. The pyridine complexes of Cu(II) and Fe(III) were found very interesting and attractive as potential candidates with antimicrobial activity. Along with this, melting point, molar conductivity measurement, magnetic moment determination, electronic and FTIR spectroscopy were also measured to characterize the prepared complexes. Pyridine acts as monodentate which resulted in formation of square planar and octahedral structure of Cu(II) and Fe(III) complexes, respectively with the nitrogen atom pyridine ring by coordination bond. Forantimicrobial activity studies Alternaria alternata, Bacillus cerelus, Botrgodiplodia theobromal, Colletotrichums corcolei, Escherichia coli, Fusarium equiseti, Macrophomina phaseolina, Salmonell typhi and Shigella dysenteriae were used. The prepared complexes showed inhibition against mycelial growth. Although the complexes showed satisfactory inhibition against the tested bacteria and fungispecies, both of the complexes were comparatively better against bacteria than fungi compared to ligand.