
Synthesis, Characterization and in vitro Antimicrobial, Antioxidant and Anticancer Activity of Random Copolyester Using 1,4-Dithiane-2,5-diol
Author(s) -
B. Kalpana,
R. Nanthini
Publication year - 2019
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2019.21997
Subject(s) - copolyester , diol , chemistry , sebacic acid , condensation polymer , cyclohexane , carbon 13 nmr , dithiane , polymer chemistry , differential scanning calorimetry , proton nmr , organic chemistry , polymer , polyester , physics , thermodynamics
A random copolyester was prepared by direct melt polycondensation method using 1,4-dithiane-2,5-diol, 1,4-cyclohexane diol and Sebacic acid in the mole ratio 1:1:2 using titanium tetra isopropoxide as catalyst. The synthesized copolyester poly(1,4-dithiane-2,5-diol sebacate–co–1,4-cyclohexane diol sebacate) (PDCSe) was characterized by FT-IR, 1H NMR and 13C NMR to determine the chemical structure, while wide angle XRD, differential scanning spectroscopy and Inherent viscosity were determined to study its physical properties. Further the antioxidant, antimicrobial and anticancer activities of the synthesized copolyester were determined to study its biological property.