Open AccessChemically Modified Hydroxyapatite Nanocrystals by Temperature-Responsive Poly(N-isopropylacrylamide) via Surface Initiated Radical Polymerization
Author(s) -
Doan Van Thuan,
Hieu-Vu Quang,
Bui Le Minh,
Phạm Văn Thinh,
Md. Rafiqul Islam,
Van Thi Thanh Ho,
Duyen Thi Cam Nguyen
Publication year - 2019
Publication title -
asian journal of chemistry/asian journal of chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.145
H-Index - 34
eISSN - 0975-427X
pISSN - 0970-7077
DOI - 10.14233/ajchem.2019.21769
Subject(s) - chemistry , polymerization , thermogravimetric analysis , poly(n isopropylacrylamide) , polymer chemistry , lower critical solution temperature , thiol , fourier transform infrared spectroscopy , surface modification , grafting , radical polymerization , nanoparticle , x ray photoelectron spectroscopy , chemical engineering , copolymer , polymer , organic chemistry , engineering
This article reports on application of surface-initiated thiol-lactam initiated radical polymerization (TLIRP) method to modify hydroxyapatite nanocrystals (HAP) with thermoresponsive poly(N-isopropylacrylamide) (PNIPAm) brushes through grafting from strategy. Initially, 3-mercaptopropyl trimethoxysilane possessing thiol groups was functionalized with the -OH species on the surface of hydroxyapatite through ligand-exchanging response to introduce thiol species on hydroxyapatite (hydroxyapatite-thiol). Subsequently, attaching polymerization of N-isopropylacrylamide from HAP-SH surface was accomplished in the attendance of butyrolactam to produce PNIPAAmg-HAP. Thermogravimetric analysis, Fourier transform infrared, X-ray photoelectron spectroscopy and their thermal phase transition behaviour were employed to confirm the grafting and to characterize the nanoparticle structure.