Open AccessEpithelial-endothelial transition and endothelial-mesenchymal transition
Author(s) -
Doménico Ribatti
Publication year - 2022
Publication title -
the international journal of developmental biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.837
H-Index - 103
eISSN - 1696-3547
pISSN - 0214-6282
DOI - 10.1387/ijdb.210234dr
Subject(s) - epithelial–mesenchymal transition , biology , mesenchymal stem cell , microbiology and biotechnology , transition (genetics) , embryonic stem cell , endothelial stem cell , epithelium , cancer research , genetics , gene , in vitro
The movement of continuous sheets of epithelial cells occurs during embryonic development, tissue repair, and cancer. Common to cellular and molecular principles of collective cell migration, invading cancers seem to reactivate embryonic pathways and patterns of cell movement. Epithelial cells possess the capability to become mesenchymal cells in a process called epithelial mesenchymal transition (EMT), which has been extensively studied and described. The aim of this article is to summarizes the most recent literature data concerning less known epithelial-endothelial transition and endothelial-mesenchymal transition.