Open AccessHaltere development in D. melanogaster: implications for the evolution of appendage size, shape and function
Author(s) -
Soumen Khan,
C Dilsha,
L. S. Shashidhara
Publication year - 2020
Publication title -
the international journal of developmental biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.837
H-Index - 103
eISSN - 1696-3547
pISSN - 0214-6282
DOI - 10.1387/ijdb.190133ls
Subject(s) - biology , appendage , ultrabithorax , hox gene , drosophila melanogaster , wing , evolutionary biology , mechanism (biology) , developmental biology , function (biology) , anatomy , microbiology and biotechnology , genetics , transcription factor , gene , philosophy , epistemology , engineering , aerospace engineering
Differential specification of dorsal flight appendages, wing and haltere, in Drosophila provides an excellent model system to address a number of important questions in developmental biology at the levels of molecules, pathways, tissues, organs, organisms and evolution. Here we discuss the mechanism by which the Hox protein Ubx recognizes and regulates its downstream targets, implications of the same in growth control at cellular and organ level and finally the evolution of haltere from ancestral hindwings in other holometabolous insects.