
Piperaquine-resistant PfCRT mutations differentially impact drug transport, hemoglobin catabolism and parasite physiology in Plasmodium falciparum asexual blood stages
Author(s) -
John Okombo,
Sachel Mok,
Tarrick Qahash,
Tomas Yeo,
Jade Bath,
Lindsey Orchard,
Edward Owen,
Imhoi Koo,
István Albert,
Manuel Llinás,
David A. Fidock
Publication year - 2022
Publication title -
plos pathogens
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.719
H-Index - 206
eISSN - 1553-7374
pISSN - 1553-7366
DOI - 10.1371/journal.ppat.1010926
Subject(s) - plasmodium falciparum , piperaquine , biology , parasite hosting , hemoglobin , plasmodium (life cycle) , malaria , virology , immunology , artemisinin , biochemistry , world wide web , computer science